Isabella M Grumbach Selected Research

Methionine Sulfoxide Reductases

1/2018	Defective protein repair under methionine sulfoxide A deletion drives autophagy and ARE-dependent gene transcription.
12/2015	Deletion of Methionine Sulfoxide Reductase A Does Not Affect Atherothrombosis but Promotes Neointimal Hyperplasia and Extracellular Signal-Regulated Kinase 1/2 Signaling.
11/2011	Oxidation of CaMKII determines the cardiotoxic effects of aldosterone.

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Isabella M Grumbach Research Topics

Disease

6	Hypertension (High Blood Pressure) 01/2021 - 02/2010
5	Heart Failure 01/2022 - 03/2010
5	Vascular System Injuries 01/2018 - 03/2011
5	Inflammation (Inflammations) 01/2017 - 01/2015
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2021 - 07/2011
4	Neointima 01/2019 - 03/2011
4	Hyperplasia 01/2018 - 03/2011
4	Asthma (Bronchial Asthma) 01/2017 - 07/2013
3	Uveal melanoma 06/2022 - 01/2021
2	Cardiomyopathies (Cardiomyopathy) 01/2022 - 11/2011
2	Neoplasms (Cancer) 12/2021 - 01/2021
2	Vascular Remodeling 01/2021 - 12/2016
2	Fibrosis (Cirrhosis) 01/2016 - 01/2015
2	Vascular Diseases (Vascular Disease) 12/2015 - 07/2011
2	Hypertrophy 02/2012 - 02/2010
1	Retinal Hemorrhage 06/2022
1	Melanoma (Melanoma, Malignant) 06/2022
1	Optic Nerve Diseases (Optic Neuropathy) 06/2022
1	Hyperemia 01/2022
1	Myocarditis (Carditis) 01/2021
1	Cardiac Arrhythmias (Arrythmia) 01/2021
1	Heart Diseases (Heart Disease) 01/2018
1	Septic Shock (Toxic Shock Syndrome) 01/2018
1	Eosinophilia 01/2017
1	Lung Diseases (Lung Disease) 01/2017
1	Pulmonary Fibrosis (Fibrosing Alveolitis) 01/2016
1	Ischemic Stroke 01/2016
1	Brain Ischemia (Cerebral Ischemia) 01/2016
1	Choristoma (Ectopic Tissue) 01/2016
1	Reperfusion Injury 01/2016
1	Thrombosis (Thrombus) 12/2015
1	Atherosclerosis 11/2015
1	Atherosclerotic Plaque (Atheroma) 11/2015
1	Airway Remodeling 01/2015
1	Myocardial Infarction 11/2011
1	Heart Rupture 11/2011
1	Cardiac Sudden Death (Sudden Cardiac Arrest) 08/2011
1	Sick Sinus Syndrome 08/2011

Drug/Important Bio-Agent (IBA)

15	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 01/2018 - 02/2010
6	Angiotensin IIIBA 01/2021 - 02/2010
6	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2019 - 07/2011
5	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2010
5	Calcium-Calmodulin-Dependent Protein KinasesIBA 02/2014 - 02/2010
3	Retinaldehyde (Retinal)IBA 06/2022 - 01/2021
3	Methionine Sulfoxide ReductasesIBA 01/2018 - 11/2011
3	Phosphotransferases (Kinase)IBA 01/2018 - 03/2011
3	Calmodulin (Calcium-Dependent Activator Protein)IBA 01/2018 - 03/2011
2	Biomarkers (Surrogate Marker)IBA 06/2022 - 01/2021
2	AntioxidantsIBA 01/2017 - 01/2015
2	Peptides (Polypeptides)IBA 01/2017 - 02/2010
2	Methionine (L-Methionine)FDA Link 01/2016 - 12/2015
2	CollagenIBA 01/2016 - 01/2015
2	ApolipoproteinsIBA 12/2015 - 11/2015
2	AllergensIBA 01/2015 - 07/2013
1	Messenger RNA (mRNA)IBA 01/2022
1	Enterotoxins (Enterotoxin)IBA 01/2018
1	SuperantigensIBA 01/2018
1	Biocompatible Materials (Biomaterials)IBA 01/2018
1	staphylococcal enterotoxin CIBA 01/2018
1	InflammasomesIBA 01/2017
1	Pharmaceutical PreparationsIBA 01/2017
1	Bleomycin (Blenoxane)FDA LinkGeneric 01/2016
1	E-SelectinIBA 01/2016
1	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 12/2015
1	Mitogen-Activated Protein Kinase 3IBA 12/2015
1	InterleukinsIBA 11/2015
1	Toll-Like Receptor 4IBA 11/2015
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2015
1	Fibronectins (Fibronectin)IBA 11/2015
1	human extra domain A fibronectinIBA 11/2015
1	Apolipoproteins E (ApoE)IBA 11/2015
1	CalciumIBA 06/2015
1	CytokinesIBA 01/2015
1	Transforming Growth Factors (Transforming Growth Factor)IBA 01/2015
1	Interleukin-13IBA 01/2015
1	PicrotoxinIBA 07/2013
1	OvalbuminIBA 07/2013
1	Sildenafil Citrate (Viagra)FDA Link 02/2012
1	Toxic ActionsIBA 11/2011
1	Isoproterenol (Isoprenaline)FDA LinkGeneric 11/2011
1	EnzymesIBA 11/2011
1	CatecholaminesIBA 11/2011
1	Adrenergic Agents (Adrenergic Drugs)IBA 11/2011
1	NADPH Oxidases (NAD(P)H oxidase)IBA 11/2011
1	AldosteroneIBA 11/2011
1	Oxidants (Oxidizing Agents)IBA 08/2011
1	Transcription Factors (Transcription Factor)IBA 02/2010
1	Histone Deacetylases (Histone Deacetylase)IBA 02/2010
1	KN 93IBA 02/2010

Therapy/Procedure

6	Therapeutics 01/2021 - 07/2011
3	Lasers (Laser) 06/2022 - 01/2021
3	Brachytherapy 06/2022 - 01/2021
3	Ligation 12/2015 - 03/2011
1	Aftercare (After-Treatment) 06/2022
1	Radiotherapy 12/2021
1	Drug Therapy (Chemotherapy) 01/2021
1	Artificial Pacemaker 08/2011